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DXC004A (Hangzhou DAC Biotechnology)
- Development stage
- Preclinical
- Lead developer
- Hangzhou DAC Biotech
- Modality
- Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
01
Overview
DXC004A (Hangzhou DAC Biotechnology): sourced facts only. name: "DXC004A is an ADC drug targeting EGFR, in which a Nimotuzumab derivative and a Tubulysin B analog is conjugated by a functional linker." [DOI:10.1158/1538-7445.am2024-4553]; target: "DXC004A is an ADC drug targeting EGFR, in which a Nimotuzumab derivative and a Tubulysin B analog is conjugated by a functional linker." [DOI:10.1158/1538-7445.am2024-4553]; developer: "1Hangzhou DAC Biotechnology Co., Ltd., Hangzhou City, China." [DOI:10.1158/1538-7445.am2024-4553]; modality: "DXC004A is an ADC drug targeting EGFR, in which a Nimotuzumab derivative and a Tubulysin B analog is conjugated by a functional linker." [DOI:10.1158/1538-7445.am2024-4553]; stage: "Meanwhile, a single injection of low-dose DXC004 (2.5 mg/kg) in HCC827 xenograft model showed very good durable anti-tumor effect." [DOI:10.1158/1538-7445.am2024-4553]
02
Targets
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