DZD9008 + carbamazepine

This is a combination of two drugs: - **Sunvozertinib (DZD9008):** An orally available, potent, irreversible small molecule inhibitor that selectively targets mutant forms of the epidermal growth factor receptor (EGFR), particularly EGFR exon 20 insertion mutations and also human epidermal growth factor receptor 2 (HER2). It is being developed primarily for non–small cell lung cancer (NSCLC) patients with EGFR exon 20 insertion mutations. Sunvozertinib has demonstrated significant anti-tumor activity and a favorable safety profile in clinical trials[1][3][5][6]. - **Carbamazepine:** A well-established small molecule anticonvulsant and mood stabilizer used primarily to treat epilepsy and neuropathic pain. Its mechanism involves inhibition of voltage-gated sodium channels in neuronal membranes.

Brand names

sunvozertinib

Other names

DZD9008DZD-9008DZD 9008sunvozertinibcarbamazepine