Drug intelligence / Profile preview

efalizumab + acitretin

Development stage
Unknown
Lead developer
Genentech
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Subcutaneous, Oral
01

Overview

A combination therapy consisting of efalizumab (a humanized monoclonal antibody against CD11a) and acitretin (a second-generation monoaromatic retinoid). This specific combination is not well-documented in the literature based on the provided search results. Acitretin is used in the treatment of psoriasis and works by normalizing epidermal cell proliferation and differentiation. Efalizumab was previously used for psoriasis but was withdrawn from the market.

02

Targets

ITGAL (Integrin alpha L (CD11a))

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