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Drug intelligence / Profile preview
Egyptian Atomic Energy Authority (EAEA) aromatase compound 10
- Development stage
- Preclinical
- Lead developer
- Egyptian Atomic Energy Authority
01
Overview
Egyptian Atomic Energy Authority (EAEA) aromatase compound 10: sourced facts only. name: "Also, compound 10 was the most potent aromatase inhibitor with the lowest IC50 (0.06 μM) compared to letrozole (IC50 0.05 μM)." [PMID:40239405]; target: "Also, compound 10 was the most potent aromatase inhibitor with the lowest IC50 (0.06 μM) compared to letrozole (IC50 0.05 μM)." [PMID:40239405]; developer: "Department of Drug Radiation Research, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo 11787, Egypt." [PMID:40239405]; stage: "Compound 10 exhibited a promising cytotoxic activity (IC50 1.83 μM) that nearly equal to the reference drug (doxorubicin, IC50 1.94 μM) on MCF-7 cells." [PMID:40239405]
02
Targets
CYP19A1 (Aromatase)
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