Drug intelligence / Profile preview

Enterococcus faecium L6 + Lactobacillus plantarum L10

Development stage: Preclinical
Lead developer: Northeast Agricultural University
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

*Enterococcus faecium* L6 + *Lactobacillus plantarum* L10 is a combination live biotherapeutic product (LBP) consisting of two specific probiotic bacterial strains. It is primarily investigated for use in the poultry industry as a sustainable alternative to antibiotic growth promoters. The therapy aims to improve growth performance and carcass yield in broilers while providing protection against Enterohemorrhagic *Escherichia coli* (EHEC) O157:H7 infections. Its mechanism of action involves the beneficial modulation of the cecal microbiota, enhancement of the intestinal mucosal barrier function, and stimulation of the host's immune and antioxidant systems. By promoting a healthy gut environment and strengthening host defenses, this combination reduces pathogen colonization and supports overall avian health.

Other names: Enterococcus faecium L6 and Lactobacillus plantarum L10 combinationL6+L10 probiotic

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