Drug intelligence / Profile preview

epinephrine + anhydrous dextrose + aspirin + albuterol sulfate + nitroglycerin + diphenhydramine

Development stage
Unknown
Lead developer
Best Dental Kit
Modality
Small Molecules
Administration
Intramuscular, Oral, Inhalation, Sublingual
01

Overview

This product is a **multi-component dental office emergency kit** that includes epinephrine, albuterol sulfate, nitroglycerin, diphenhydramine hydrochloride, aspirin, and glucose tablets, with **anhydrous dextrose present as part of the epinephrine formulation/excipient context rather than as the principal named drug moiety of the kit**. It is marketed in the United States as the **Basic Dental Emergency Kit** and **Deluxe Dental Emergency Kit** and is listed on DailyMed by Best Dental Kit for in-office management of acute medical emergencies such as **anaphylaxis and other type I allergic reactions, bronchospasm, angina or suspected acute coronary symptoms, non-life-threatening allergic reactions, and hypoglycemia**. Mechanistically, the kit combines a **non-selective alpha- and beta-adrenergic agonist** for anaphylaxis rescue, a **beta-2 adrenergic receptor agonist bronchodilator** for acute bronchospasm, a **nitric oxide-donating vasodilator** for angina, an **H1 antihistamine** for allergic symptoms, **aspirin** for analgesic and antiplatelet use, and **oral glucose** for low blood sugar rescue. The overall modality is best characterized as a **small-molecule combination pharmaceutical kit** assembled for emergency preparedness in dental practice settings rather than as a single novel molecular entity.

Brand names
Basic Dental Emergency KitDeluxe Dental Emergency Kit
Other names
epinephrine + anhydrous dextrose + aspirin + albuterol sulfate + nitroglycerin + diphenhydramineepinephrine + aspirin + albuterol sulfate + nitroglycerin + diphenhydramine
02

Targets

HRH1 (Histamine H1 Receptor)ADRA2A (α2A)ADRA1A (α1A)ADRB2 (β2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)sGC (Soluble Guanylyl Cyclase)PGHS-1 (Prostaglandin G/H Synthase 1)ADRB1 (β1)

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