Drug intelligence / Profile preview

erector spinae plane block + serratus anterior plane block

Development stage
Preclinical
Lead developer
Bursa City Hospital
Modality
Small Molecules
Administration
Perineural
01

Overview

This intervention is a combination of two regional anesthetic techniques, the Erector Spinae Plane Block (ESPB) and the Serratus Anterior Plane Block (SAPB), utilized for the management of acute pain following a thoracotomy. In a clinical trial conducted by Bursa City Hospital, both blocks are performed using 0.25% bupivacaine. The ESPB involves injecting local anesthetic into the fascial plane deep to the erector spinae muscle, typically at the T4-T5 level, to target the dorsal and ventral rami of spinal nerves. The SAPB involves injection into the fascial plane around the serratus anterior muscle, usually at the 5th-6th rib level, targeting the lateral cutaneous branches of the intercostal nerves. Together, these blocks aim to provide comprehensive analgesia of the thoracic wall, potentially reducing postoperative opioid consumption and associated complications.

Other names
erector spinae plane block + serratus anterior plane block-Bursa City Hospital-post-thoracotomy painESPB + SAPBErector spinae plane block combined with serratus anterior plane block
02

Targets

NaV (Voltage-gated sodium channels)

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