Drug intelligence / Profile preview

ergocalciferol + cholecalciferol (Laboratorio Domínguez)

Development stage
Unknown
Lead developer
Laboratorio Domínguez
Modality
Small Molecules
Administration
Oral
01

Overview

Laboratorio Dominguez markets two Vitamin D supplements under the DENURIX brand: DENURIX (ergocalciferol/Vitamin D2) and DENURIX D3 (cholecalciferol/Vitamin D3). These oral small molecule supplements act as agonists of the Vitamin D receptor (VDR). Upon ingestion, they are metabolized to their active forms (e.g., calcitriol), which bind to the VDR in the nucleus of target cells. This activation regulates calcium and phosphate homeostasis, promoting intestinal calcium absorption and maintaining bone mineralization. They are indicated for the treatment and prevention of Vitamin D deficiency and the management of osteoporosis in Argentina.

Brand names
DENURIXDENURIX D3
Other names
Vitamin D2Vitamin D3
02

Targets

VDR (Vitamin D receptor)

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