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Ergoferon (Materia Medica Holding)

Development stage
Phase 3
Lead developer
Materia Medica Holding
Modality
Antibody-Based Therapeutics
Administration
Oral
01

Overview

MMH-407, commercially known as **Ergoferon**, is a multi-component antiviral and anti-inflammatory drug developed by the Russian company **Materia Medica Holding**. It is composed of "release-active" (highly diluted) affinity-purified antibodies directed against three specific targets: human interferon-gamma (IFN-γ), the CD4 receptor, and histamine. The drug is designed to treat and prevent influenza and other acute respiratory viral infections (ARVI) by modulating the functional activity of these targets, thereby enhancing the body's antiviral immune response and reducing allergic-like inflammatory reactions. While it is marketed and clinically studied in Russia and several CIS countries, its pharmacological mechanism—based on dilutions that exceed the Avogadro limit—remains a subject of scientific debate within the international community.

Brand names
Ergoferon
Other names
ЭргоферонRelease-active antibodies to IFN-gamma, CD4, and histamine
02

Targets

CD4 (T lymphocyte surface antigen)IFNG (Interferon gamma)

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