Drug intelligence / Profile preview

erythromycin thiocyanate + sulfadiazine + trimethoprim

Development stage
Unknown
Lead developer
Navana Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Erazine (also known as Erazine Vet) is a veterinary combination antibiotic formulation developed by Navana Pharmaceuticals. It contains three active ingredients: erythromycin thiocyanate (a macrolide antibiotic), sulfadiazine (a sulfonamide antibiotic), and trimethoprim (a dihydrofolate reductase inhibitor). This combination provides synergistic, broad-spectrum antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, as well as Mycoplasma species. It is primarily indicated for the treatment of respiratory, gastrointestinal, and urogenital tract infections in poultry, calves, foals, and pigs, including conditions such as salmonellosis, colibacillosis, mycoplasmosis, fowl cholera, and infectious coryza.

Brand names
Erazine
Other names
erythromycin + sulfadiazine + trimethoprimerythromycin thiocyanate + sulfadiazine + trimethoprim
02

Targets

Bacterial 50S ribosomal subunitDHFR (Dihydrofolate reductase)DHPS (Dihydropteroate synthase)

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