escitalopram + eszopiclone

This is a **combination of escitalopram**, a selective serotonin reuptake inhibitor (SSRI), and **eszopiclone**, a non-benzodiazepine hypnotic agent. Escitalopram increases serotonin levels in the brain by inhibiting its reuptake, primarily used for major depressive disorder and generalized anxiety disorder. Eszopiclone is a GABA-A receptor positive allosteric modulator, used to treat insomnia by enhancing central nervous system inhibition to promote sleep. This combination is explored for patients with comorbid generalized anxiety disorder and insomnia, with studies showing that coadministration improves sleep, daytime functioning, anxiety, and mood compared to escitalopram monotherapy. The combination is generally well tolerated, though increased CNS depression (such as somnolence, dizziness, and confusion) may occur[1][3][5][6].

Brand names

LunestaLexapro

Other names

escitalopram and eszopicloneescitalopram plus eszopiclone