esomeprazole + amoxicillin + clarithromycin

**Esomeprazole + amoxicillin + clarithromycin** is a fixed-dose oral combination therapy used primarily for the *eradication of Helicobacter pylori* in patients with peptic ulcer disease and to reduce the risk of ulcer recurrence. **Esomeprazole** is a proton pump inhibitor that reduces gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase in gastric parietal cells. **Amoxicillin** is a penicillin-class beta-lactam antibiotic that exerts bactericidal activity by inhibiting bacterial cell wall synthesis. **Clarithromycin** is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Together, these agents eradicate H. pylori through different mechanisms and promote healing of gastric and duodenal ulcers. This triple therapy is often prescribed as a kit or pack, with the ingredients taken together as directed[1][2][4][5][7].

Brand names

Sompraz HPNexpro HPSpacirab-HPEsomac HZosa-HPEsoable HPEsium-HPSombrex HPEsotrend HPEsovil HPEsomeprazole Sandoz Hp7

Other names

amoxicillin + clarithromycin + esomeprazoleclarithromycin + esomeprazole + amoxicillin