estradiol + estriol + progesterone

This is a combination hormone therapy containing three bioidentical hormones: estradiol (an estrogen), estriol (another type of estrogen), and progesterone (a progestogen). While combinations of estradiol and progesterone are FDA-approved for treating menopausal symptoms such as hot flashes, the specific triple combination of estradiol + estriol + progesterone is not mentioned in the search results as an FDA-approved formulation. Estrogens generally work by replacing hormones that decline during menopause, while progesterone helps protect the uterine lining from overgrowth that could lead to cancer when taking estrogen alone.