estradiol + progesterone

**Estradiol + progesterone** is a fixed-dose oral menopausal hormone therapy developed as **Bijuva** and marketed as **Bijuve** in the United Kingdom. It combines bioidentical 17β-estradiol, an estrogen receptor agonist that replaces declining endogenous estrogen after menopause, with micronized progesterone, a progesterone receptor agonist that counteracts estrogen-driven endometrial proliferation in women with an intact uterus. The product is indicated for treatment of moderate-to-severe vasomotor symptoms due to menopause and is supplied as an immediate-release softgel capsule containing estradiol and progesterone.

Brand names

BijuvaBijuve

Other names

estradiol + micronized progesteroneestradiol and progesterone