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estradiol valerate + cyproterone acetate
- Development stage
- Unknown
- Lead developer
- Bayer HealthCare Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Estradiol valerate + cyproterone acetate is a combination hormone therapy medication that pairs an estrogen (estradiol valerate) with an antiandrogen and progestin (cyproterone acetate). This combination is primarily used for hormone replacement therapy in menopausal women and treatment of androgen-dependent conditions. Estradiol valerate is a prodrug of estradiol that improves oral bioavailability, while cyproterone acetate blocks androgen receptors and has progestogenic effects. The medication is typically administered in a sequential regimen.
- Brand names
- ClimenEstelle-35Estelle35Estelle 35Estelle-35 EDEstelle35 EDEstelle 35 ED
- Other names
- 克龄蒙
02
Targets
ESR1 (ERα)PR (Progesterone receptor)ESR2 (ERβ)AR (Adrenergic receptors)
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