Drug intelligence / Profile preview

estradiol valerate + cyproterone acetate

Development stage
Phase 4
Lead developer
Bayer
Modality
Small Molecules
Administration
Oral
01

Overview

Estradiol valerate + cyproterone acetate is a combination hormone therapy medication that pairs an estrogen (estradiol valerate) with an antiandrogen and progestin (cyproterone acetate). This combination is primarily used for hormone replacement therapy in menopausal women and treatment of androgen-dependent conditions. Estradiol valerate is a prodrug of estradiol that improves oral bioavailability, while cyproterone acetate blocks androgen receptors and has progestogenic effects. The medication is typically administered in a sequential regimen.

Brand names
ClimenEstelle-35Estelle35Estelle 35Estelle-35 EDEstelle35 EDEstelle 35 ED
Other names
克龄蒙
02

Targets

AR (Adrenergic receptors)ESR1 (ERα)ESR2 (ERβ)PR (Progesterone receptor)

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