Drug intelligence / Profile preview

ET-01 (Entheos Labs)

Development stage
Preclinical
Lead developer
Entheos Labs
Modality
Small Molecules
01

Overview

ET-01 is a synthetic small molecule derivative of a natural product being developed by Entheos Labs as a potent 5-hydroxytryptamine receptor 2A (5HT2A) agonist. Designed to promote neuroplasticity, ET-01 is the lead asset in Entheos Labs' pipeline for the treatment of various mental health conditions, including mood disorders, anxiety disorders, trauma-based disorders, and substance use disorders. The drug is being developed using a novel formulation and delivery method, leveraging an AI-powered drug discovery platform in collaboration with Massachusetts General Hospital (MGH) to optimize safety, tolerability, and user experience.

02

Targets

HTR2A (Serotonin receptor 5-HT2A)

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