Drug intelligence / Profile preview

ethinyl estradiol + norelgestromin

Development stage
Phase 4
Lead developer
OMJ Pharmaceuticals
Modality
Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Small Molecules
Administration
Transdermal
01

Overview

Ethinyl estradiol + norelgestromin is a transdermal contraceptive patch containing two active hormones: ethinyl estradiol (an estrogen) and norelgestromin (a progestin). It is primarily used for the prevention of pregnancy. The patch works by inhibiting ovulation (preventing the release of an egg from the ovary), thickening cervical mucus to block sperm entry into the uterus, and altering the endometrial lining to reduce the likelihood of implantation. The medication is applied as a skin patch once weekly for three consecutive weeks followed by a one-week patch-free interval. It may be less effective in individuals with a body weight over 198 pounds (90 kg) or BMI ≥30 kg/m²[1][2][3][4][5]. Common side effects include headache, nausea, breast tenderness, and irregular uterine bleeding.

Brand names
Ortho EvraXulaneZafemyEvra
Other names
norelgestromin/ethinylestradiolnorelgestromin-ethinyl estradiol
02

Targets

PR (Progesterone receptor)ER (Estrogen receptor)

Beyond the preview

Go deeper on ethinyl estradiol + norelgestromin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on ethinyl estradiol + norelgestromin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call