ethinylestradiol + gestodene (Schering AG)

Ginesse is a combined oral contraceptive containing the synthetic estrogen ethinylestradiol and the third-generation synthetic progestin gestodene. It is indicated for the prevention of pregnancy (contraception). Ethinylestradiol acts as an agonist of the estrogen receptors (ERα and ERβ), while gestodene acts as a potent agonist of the progesterone receptor (PR). Together, these hormones suppress the secretion of gonadotropins (luteinizing hormone and follicle-stimulating hormone) from the pituitary gland, thereby preventing ovulation, altering the cervical mucus to inhibit sperm penetration, and modifying the endometrium to prevent implantation. Ginesse is marketed by Deutsche Pharma in Chile.

Brand names

Ciclomex 20Ciclomex20Ciclomex-20Feminol 20Feminol20Feminol-20FemodeneGinesseGyneraHarmonetLindynetteLogestMelianeMelodeneMinesseMinuletMirelleTamisa 20/75

Other names

EE/GSDethinyl estradiol + gestodeneethinyloestradiol + gestodenegestodene + ethinyl estradiolgestodene + ethinylestradiolgestodene + ethinyloestradiol