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Overview MonoStep is a monophasic combined oral contraceptive developed by Jenapharm (a subsidiary of Bayer). It is a fixed-dose combination of the synthetic estrogen ethinylestradiol (30 mcg) and the synthetic progestin levonorgestrel (125 mcg). MonoStep prevents pregnancy primarily by suppressing ovulation through the inhibition of gonadotropin secretion from the pituitary gland. Additionally, it thickens cervical mucus to inhibit sperm penetration and alters the endometrium to prevent implantation. It is administered orally on a 21-day active pill cycle followed by a 7-day pill-free interval.
Brand names Afirmelle Alesse Almina 28 Almina28 Almina-28 Altavera Alysena Amethia Amethyst Anubis Ashlyna Aubra Aubra EQ Ava 30 ED Ava30 ED Ava-30 ED Aviane Ayuna Balcoltra Besafe Camrese Camrese Lo Cecil Chateal Chateal EQ Choice Cretradiol Cybelle Daysee Delyla Dolishale Dos dias n Eleanor Eleonore Elifemme Enpresse Erlidona Evelea md Evelyn ed Falmina Fayosim Femexin Femme Femme tab ed Follimin Forlady Iclevia Imediat Introvale Jaimiess Jolessa Joyeaux Kurvelo Lenest 20 ED Lenest20 ED Lenest-20 ED Lenest 30 ED Lenest30 ED Lenest-30 ED Lessina Leverette Levlen Levlen ed Levlite Levomin Levonest Levora Levostrol Lo/ovral Loette Loette 28 Loette28 Loette-28 Logynon Logynon ED LoJaimiess Lovette Lutera Lybrel Maexeni Marlissa Melleva Microfem max Microgynon Microgynon 30 Microgynon30 Microgynon-30 Microgynon ED Micronelle ed Microvlar Minisiston Minzoya Mirabella Miranova MonoStep Myzilra Nordette Nordiol Norfen Norgylen Oralcon Orsythia Ovreena Ovranette Portia Quasense Rigevidon Seasonale Seasonique Selina Selina gynial Selly gynial Setlakin Simpesse Sronyx Tetragynon Trionetta Triphasil Triquilar Trivora Twirla Tyblume Vienva Vilora
Other names EE/LNG ethinyl estradiol + levonorgestrel ethinylestradiol and levonorgestrel ethinylestradiol/levonorgestrel levonorgestrel + ethinylestradiol levonorgestrel and ethinyl estradiol 02
Targets PR (Progesterone receptor) ESR2 (ERβ) AR (Adrenergic receptors) ESR1 (ERα)
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