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etofylline + theophylline (T Walker's Pharmaceuticals)
- Development stage
- Unknown
- Lead developer
- Walker's Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Intravenous, Intramuscular
01
Overview
Twafyline (etofylline + theophylline) is a combination bronchodilator injection developed and marketed by Walker's Pharmaceuticals. It contains etofylline and theophylline, which are methylxanthine derivatives. The combination is indicated for the treatment and prevention of bronchospasm associated with asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). Etofylline and theophylline work synergistically to relax the smooth muscles of the bronchial passages and widen the airways, thereby improving airflow and relieving symptoms such as wheezing, shortness of breath, and chest tightness.
- Brand names
- AcethamaBroncasmaDeriphyllinEtifyIntaphyllineTwafyline
- Other names
- etofylline and theophyllineetofylline/theophyllineetophylline + theophyllineetophylline and theophyllineetophylline/theophylline
02
Targets
ADORA2A (Adenosine A₂A Receptor)PDE (Phosphodiesterase family)ADORA1 (Adenosine receptor A1 subtype)ADORA2B (Adenosine A2B receptor)
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