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Etoril P is a fixed-dose combination analgesic developed and marketed by Solis Pharms for pain management. It contains **etoricoxib**, a selective cyclooxygenase-2 (COX-2) inhibitor, and **paracetamol** (acetaminophen), a non-opioid analgesic and antipyretic. Etoricoxib provides anti-inflammatory and analgesic effects by specifically inhibiting the COX-2 enzyme, which is responsible for prostaglandin synthesis at sites of inflammation, while sparing the COX-1 enzyme associated with gastrointestinal protection. Paracetamol complements this by providing additional pain relief and fever reduction, likely through central nervous system mechanisms. The combination is typically indicated for the symptomatic relief of acute pain, osteoarthritis, rheumatoid arthritis, and other musculoskeletal conditions where both anti-inflammatory and analgesic actions are required.
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