etretinate + triamcinolone acetonide

This is a combination drug consisting of etretinate and triamcinolone acetonide. **Etretinate** is a second-generation synthetic aromatic retinoid used primarily for the treatment of severe psoriasis and other keratinization disorders. Its mechanism involves binding to retinoic acid receptors (RARs), acting as an agonist to modulate gene expression involved in cell differentiation and proliferation, particularly affecting keratinocytes[2][3][6]. Etretinate was withdrawn from several markets due to its long half-life and risk of teratogenicity but remains notable for its efficacy in dermatological conditions[2][6]. **Triamcinolone acetonide** is a synthetic corticosteroid with anti-inflammatory, immunosuppressive, and antipruritic properties. It acts by binding to glucocorticoid receptors, inhibiting inflammatory mediators and suppressing immune responses.

Other names

etretinate + triamcinolone acetonideRo 10-9359 + triamcinolone acetonide