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Exosomes and Stem Cells (Inteligex collaboration)

Development stage
Preclinical
Lead developer
NurExone Biologic
Modality
Stem Cell Therapies → Cell Therapies, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intranasal, Inhalation, Intravenous, Subcutaneous, Oral, Intrathecal, Intratumor, Intraarticular, Intraperitoneal
01

Overview

NurExone Biologic is developing a hybrid therapy in collaboration with Inteligex Inc. for the treatment of chronic spinal cord injury (SCI) and other traumatic injuries of the central nervous system (CNS). This program utilizes NurExone's proprietary ExoTherapy platform, which employs exosomes as nanocarriers to deliver stem cell-based treatments or stem-cell-derived components to injured tissues. The therapy is specifically designed to address the complex pathophysiology of chronic injury, including inflammation, cell death, and scar tissue formation, which differ from the challenges of acute injury. The program aims to promote neural repair and functional recovery. In 2023, the project received a grant from the Israel Innovation Authority as part of the Israel-Canada bilateral Eureka program and is currently in preclinical development.

Other names
exosome-based stem cell delivery system
02

Targets

PTEN (Phosphatase and tensin homolog deleted on chromosome ten)

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