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fecal microbiota transplant (Griffin Hospital)
- Development stage
- Unknown
- Lead developer
- Griffin Hospital
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Fecal microbiota transplant is an investigational biologic therapy being evaluated for the treatment of multiple sclerosis (MS) in a pilot study conducted by Griffin Hospital. [3, 4] The treatment involves the administration of 30 oral capsules containing fecal material from healthy donors. [3, 4] The therapeutic goal is to modify the gut microbiota composition in MS patients, which is believed to influence immune function and potentially slow the inflammatory processes involved in MS progression. [5, 6, 7] This approach is based on observations that the gut microbiome is altered in individuals with MS. [7]
- Other names
- fecal microbial transplant-Griffin Hospital-multiple sclerosisOral FMTfecal microbial transplant
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