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Fecal microbiota transplantation (Shanghai 10th People's Hospital)
- Development stage
- Unknown
- Lead developer
- Shanghai Tenth People's Hospital
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Fecal microbiota transplantation (FMT) from Shanghai 10th People's Hospital is a microbial therapy being investigated for the treatment of inflammatory bowel diseases (IBD), specifically ulcerative colitis and Crohn's disease. The therapy involves the administration of donor-derived functional microbes, formulated into oral capsules, to restore intestinal microbial diversity and resolve dysbiosis. In clinical studies, this FMT preparation is being evaluated both as a monotherapy and in combination with biological agents like infliximab to improve clinical remission rates and remodel the intestinal flora in patients who have failed prior biological treatments.
- Other names
- fecal microbiota transplantation capsulesintestinal bacterial transplant capsule therapy
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