Drug intelligence / Profile preview

fentanyl + lidocaine + bupivacaine + hyaluronidase

Development stage
Unknown
Lead developer
Cairo University
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Ophthalmic
01

Overview

This drug is a multi-component local anesthetic mixture used for peribulbar block in ophthalmic surgeries, specifically anterior segment procedures. It combines two amide-type local anesthetics, **lidocaine** (fast-onset) and **bupivacaine** (long-acting), with **hyaluronidase**, an enzyme that acts as a spreading agent to enhance the dispersion of the anesthetics through the orbital tissues. **Fentanyl**, a potent synthetic opioid, is added as an adjuvant to enhance the quality of the block, provide supplemental analgesia, and potentially prolong the duration of postoperative pain relief. The mixture is typically administered via peribulbar injection to achieve akinesia and anesthesia of the eye.

Other names
fentanyl + lidocaine + bupivacaine + hyaluronidase mixturefentanyl adjuvant peribulbar block
02

Targets

NaV (Voltage-gated sodium channels)MOR (Mu opioid receptor)

Beyond the preview

Go deeper on fentanyl + lidocaine + bupivacaine + hyaluronidase.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on fentanyl + lidocaine + bupivacaine + hyaluronidase.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call