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Siobion is a hematinic supplement developed and marketed by Sampharindo Putra Trading (Sampharindo Perdana). It is formulated as a combination of ferrous fumarate, manganese sulfate, copper sulfate, ascorbic acid (Vitamin C), folic acid, and cyanocobalamin (Vitamin B12). The product is primarily indicated for the treatment and prevention of iron-deficiency anemia, particularly during periods of increased demand such as pregnancy, lactation, and recovery from illness. Ferrous fumarate provides a source of elemental iron for hemoglobin synthesis, while folic acid and Vitamin B12 are essential co-factors for DNA synthesis and erythropoiesis. The inclusion of Vitamin C enhances the gastrointestinal absorption of iron, and trace minerals like copper and manganese support various enzymatic processes related to blood cell formation.
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