ferrous sulfate + serine

Aktiferrin is an oral antianemic combination therapy consisting of ferrous sulfate and the amino acid D,L-serine. It is indicated for the treatment of iron deficiency and iron deficiency anemia of various etiologies, including latent iron deficiency and nutritional anemia. The inclusion of serine is designed to enhance the absorption of iron in the gastrointestinal tract and improve gastrointestinal tolerability, which potentially allows for lower effective doses of iron compared to standard ferrous sulfate preparations. The drug is available in multiple oral formulations, including capsules, syrup, and drops. It has been investigated in clinical settings, such as a Phase 2 trial evaluating alternate-day versus consecutive-day dosing in post-bariatric surgery patients to optimize hemoglobin and ferritin response.

Brand names

Aktiferrin

Other names

ferrous sulfate/serineiron sulfate + serine