ferulic acid + angelica archangelica extract

Ferulic acid + angelica archangelica extract is a **dietary supplement** consisting of 200 mg ferulic acid and 40 mg Angelica archangelica extract per daily dose, branded as Feru-guard. Ferulic acid is a phytochemical found in plant cell walls, known for **antioxidant, anti-inflammatory, and neuroprotective actions**, such as decreasing free radicals, chronic inflammation, and beta-secretase transcription, leading to reduced amyloid-beta (Aβ) aggregation and neuronal loss. Angelica archangelica root extract has been reported to inhibit acetylcholinesterase and provide antioxidative effects. This combination has shown statistically significant cognitive improvement in people with **mild cognitive impairment (MCI)** in multicenter randomized controlled trials, improving Mini-Mental State Examination (MMSE) and ADAS-Jcog scores at several weeks of supplementation. The developer and manufacturer is Glovia. No serious adverse events have been reported in large populations. Mechanistically, ferulic acid destabilizes Aβ fibrils and inhibits aggregation, while Angelica offers acetylcholinesterase inhibition, antioxidant, and anti-inflammatory actions[1][2][3][4].

Brand names

Feru-guard

Other names

Feru-guardFG 100 MFG100 MFG-100 M