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fexofenadine hydrochloride + sodium lauryl sulfate
- Development stage
- Preclinical
- Lead developer
- Dr. Reddy's Laboratories
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
This is a combination of fexofenadine hydrochloride, a second-generation non-sedating antihistamine, and sodium lauryl sulfate (SLS), an excipient commonly used in pharmaceutical formulations. Fexofenadine acts as a selective antagonist at the histamine H1 receptor, blocking the action of endogenous histamine and thereby reducing symptoms associated with allergic rhinitis and chronic idiopathic urticaria such as sneezing, rhinorrhea, itchy nose/palate/throat, and itchy/watery/red eyes. Sodium lauryl sulfate is not pharmacologically active but may be included to modify drug absorption or tablet dissolution properties. This specific combination has been studied to assess whether SLS affects the absorption of fexofenadine in humans[5][6].
- Other names
- fexofenadine HCl + SLSfexofenadine hydrochloride with sodium lauryl sulfate
02
Targets
HRH1 (Histamine H1 Receptor)
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