Drug intelligence / Profile preview

fibrin glue + normal saline

Development stage
Unknown
Lead developer
Baxter Healthcare Corporation
Administration
Topical
01

Overview

Fibrin glue + normal saline is a combination used in surgical settings. Fibrin glue (also called fibrin sealant) is a surgical formulation containing human fibrinogen and human thrombin that creates a fibrin clot for hemostasis, wound healing, and tissue adhesion. When combined with normal saline, it has been shown to have specific applications in certain surgical procedures. In skin grafting, this combination has demonstrated decreased wound contraction compared to controls, likely due to increased adherence of grafts to the underlying wound bed. The normal saline component may help in the application and distribution of the fibrin glue across the surgical site.

02

Targets

Fibrin (Factor Ia)

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