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Fimasartan + indapamide is a fixed-dose combination of two antihypertensive agents used to treat high blood pressure (hypertension). Fimasartan is an angiotensin II receptor antagonist (ARB) that selectively blocks the type 1 angiotensin II receptor, leading to vasodilation, reduced aldosterone secretion, and decreased blood volume. This results in lower blood pressure and protective effects against cardiovascular events such as stroke and heart failure[2][6]. Indapamide is a thiazide-like diuretic that promotes sodium and water excretion by inhibiting sodium reabsorption in the distal tubules of the kidney, thereby reducing fluid retention and lowering blood pressure[1][3]. The combination targets different mechanisms involved in hypertension for additive or synergistic antihypertensive effects.
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