Drug intelligence / Profile preview

fIPV + RotaTeq

Development stage
Unknown
Lead developer
Merck
Modality
Vaccines & Immunotherapeutics
Administration
Intradermal, Oral
01

Overview

fIPV + RotaTeq refers to the concomitant administration of a fractional dose of inactivated poliovirus vaccine (fIPV) and the pentavalent rotavirus vaccine RotaTeq. This regimen involves the intradermal delivery of 0.1 mL (one-fifth of a full dose) of IPV alongside the oral administration of RotaTeq. The combination has been primarily evaluated in clinical trials in low-resource settings, such as Bangladesh, to optimize vaccination schedules and address IPV supply shortages. RotaTeq, developed by Merck, contains five live human-bovine reassortant rotaviruses (G1, G2, G3, G4, and P1A[8]) to prevent rotavirus gastroenteritis, while fIPV provides protection against paralytic poliomyelitis caused by poliovirus types 1, 2, and 3.

Other names
fractional inactivated poliovirus vaccine + RotaTeqfIPV + RV5fIPV + pentavalent rotavirus vaccine
02

Targets

RVA (Rotavirus A)

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