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A combination therapy composed of **fish oil enriched with eicosapentaenoic acid (EPA)** and **orlistat**. Fish oil is a dietary supplement high in omega-3 fatty acids, particularly EPA, which is known to lower triglyceride levels and exert anti-inflammatory effects[4]. Orlistat is a **pharmaceutical gastrointestinal lipase inhibitor** used for weight management by reducing the absorption of dietary fat in the gastrointestinal tract[3]. This combination targets both dyslipidemia (mainly hypertriglyceridemia, via fish oil/EPA) and excess body weight (via orlistat), making it potentially useful in metabolic diseases or comorbid hyperlipidemia and obesity[2]. There is no evidence of direct pharmacokinetic or pharmacodynamic interaction between the two agents[1].
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