Drug intelligence / Profile preview

FLU-Q-PAN H7N9 Formulation 3 + AS03A

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This product is a **combination pandemic influenza vaccine** consisting of an inactivated, split-virion H7N9 influenza antigen (FLU-Q-PAN H7N9 Formulation 3) mixed with the **AS03A oil-in-water adjuvant system**. The vaccine is designed for enhanced immunogenicity against avian influenza A(H7N9), a virus with pandemic potential. The inclusion of the AS03A adjuvant significantly improves the body's immune response to the otherwise poorly immunogenic H7 hemagglutinin antigen. The adjuvant (AS03A) contains squalene, DL-α-tocopherol, and polysorbate 80, and is known to broaden and augment the antibody response to the vaccine. The primary indication is the **prophylaxis of influenza A(H7N9) infection** in adults and children. This vaccine formulation is designed to be mixed at the point of use, allowing for rapid deployment during a pandemic.

Brand names
FLU-Q-PAN H7N9 Formulation 3 + AS03A
02

Targets

HA (Hemagglutinin)

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