flucloxacillin (Navesta Pharmaceuticals)

Uniflox is a brand name for flucloxacillin, a narrow-spectrum beta-lactam antibiotic of the penicillin class, specifically categorized as a penicillinase-resistant penicillin. Manufactured by Navesta Pharmaceuticals, it is indicated for the treatment of bacterial infections caused by Gram-positive organisms, particularly penicillinase-producing staphylococci. Flucloxacillin exerts its antibacterial effect by binding to penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. This binding inhibits the transpeptidation enzymes responsible for cross-linking peptidoglycan chains, thereby disrupting cell wall synthesis and leading to bacterial cell lysis. Uniflox is typically administered orally and is available in a 500 mg capsule dosage form.

Brand names

Uniflox

Other names

floxacillin