fluconazole + famitinib

This is a combination of two small molecule drugs: **Fluconazole** is a triazole antifungal agent that inhibits fungal cytochrome P450 enzyme 14α-demethylase, thereby blocking the conversion of lanosterol to ergosterol, an essential component of the fungal cell membrane. It is primarily used to treat systemic and superficial fungal infections, including candidiasis and cryptococcal meningitis[1][4]. **Famitinib** is an orally active tyrosine kinase inhibitor targeting multiple receptor tyrosine kinases such as vascular endothelial growth factor receptors 2/3, platelet-derived growth factor receptor, stem cell factor receptor (c-Kit), FMS-like tyrosine kinases Flt1 and Flt3. It has antitumor activity by inhibiting tumor angiogenesis and proliferation. Developed for advanced solid tumors including colorectal cancer, non-small cell lung cancer, gastrointestinal stromal tumors, cervical cancer, endometrial cancer, nasopharyngeal carcinoma and others[6][8][10]. The combination has been studied in drug-drug interaction trials in healthy subjects[2].

Brand names

艾比特Aibite

Other names

TriflucanDifluconazoleFluconazolumFamitinib maleate