fluorescein sodium + benoxinate hydrochloride

Fluorescein sodium + benoxinate hydrochloride is a fixed-dose combination ophthalmic solution used primarily for diagnostic and minor therapeutic procedures in the eye. It combines fluorescein sodium, a disclosing (staining) agent that highlights corneal defects or foreign bodies under blue light, with benoxinate hydrochloride, a local ester anesthetic that provides rapid-onset but short-duration topical anesthesia. This combination facilitates procedures such as tonometry, gonioscopy, removal of corneal foreign bodies, and fitting of hard contact lenses by both staining the ocular surface and numbing the eye to reduce discomfort[1][2][3][4][5]. The product is available in various strengths (commonly 0.25–0.3% fluorescein sodium with 0.4% benoxinate hydrochloride)[1][2][6]. Prolonged use may cause corneal toxicity; it is contraindicated in patients with hypersensitivity to any component[4].

Brand names

FluressFluroxAltafluor Benox

Other names

fluorescein sodium and benoxinate hydrochloride ophthalmic solutionfluorescein sodium / benoxinate HCl