fluoride + silica + isopropylmethylphenol

Fluoride + silica + isopropylmethylphenol is an experimental toothpaste formulation developed by GSK for the treatment and prevention of gingivitis. The formulation utilizes a silica-based abrasive system for mechanical plaque removal and fluoride (likely sodium fluoride) for the remineralization of tooth enamel and prevention of dental caries. A key active component is isopropylmethylphenol (IPMP, also known as o-Cymen-5-ol), an antimicrobial agent that targets oral bacteria to maintain gingival health and reduce inflammation. The development of this specific formulation was evaluated in a Phase 1 clinical trial designed to measure its efficacy over 24 weeks, though the study was ultimately withdrawn before completion.

Other names

o-Cymen-5-olo-Cymen5-olo-Cymen 5-olisopropylmethylphenolIPMP