fluoride + sodium fluoride

Fluoride + sodium fluoride refers to a specific combination therapy evaluated for the prevention and remineralization of dental white spot lesions and caries, particularly in orthodontic patients. This regimen involves the application of MI Varnish, a 5% sodium fluoride treatment, in conjunction with MI Paste Plus, a topical cream containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride. The mechanism of action involves the delivery of fluoride, calcium, and phosphate ions to the tooth surface, where they promote the formation of fluorapatite and stabilize amorphous calcium phosphate, thereby enhancing the remineralization of hydroxyapatite and increasing the enamel's resistance to acid-induced demineralization.

Brand names

MI VarnishMI Paste Plus

Other names

casein phosphopeptide-amorphous calcium phosphate + fluoride