fluorometholone + rebamipide

Fluorometholone + rebamipide is a combination ophthalmic formulation intended for topical use in the eye. Fluorometholone is a synthetic adrenocorticosteroid with potent anti-inflammatory properties, commonly used as an ophthalmic suspension to treat ocular inflammation. It acts primarily by inhibiting multiple inflammatory cytokines and mediators, thereby reducing swelling, redness, and discomfort in ocular tissues[1][3]. Rebamipide is a mucosal protective agent originally developed for gastrointestinal conditions but has also been formulated as an ophthalmic solution or suspension. Its mechanism involves stimulating prostaglandin production and enhancing mucin secretion on the ocular surface, which promotes epithelial healing and protects against damage from inflammation or dryness[2][5]. The combination aims to provide both anti-inflammatory effects (from fluorometholone) and enhanced epithelial protection/healing (from rebamipide), making it suitable for treating various inflammatory or injury-related eye conditions where both actions are beneficial[4].