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fluticasone + theophylline
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Inhalation, Oral
01
Overview
Fluticasone + theophylline is a combination therapy used in respiratory medicine. Fluticasone is a corticosteroid with anti-inflammatory properties, while theophylline is a bronchodilator that belongs to the methylxanthine class. This combination may provide enhanced therapeutic effects in asthma management through complementary mechanisms of action. Fluticasone reduces airway inflammation while theophylline provides bronchodilation and may enhance corticosteroid effects through histone deacetylase activation.
02
Targets
PDE4 (Phosphodiesterase 4A1)GR (Glucocorticoid receptor)PDE3ADORA1 (Adenosine receptor A1 subtype)
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