Drug intelligence / Profile preview

fluticasone propionate + vilanterol

Development stage
Phase 4
Lead developer
GSK
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Inhalation
01

Overview

Fluticasone propionate + vilanterol is a fixed-dose combination inhalation medication used for the long-term maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It is indicated when symptoms are not adequately controlled with other asthma medications or when more than one daily medicine is required. Fluticasone propionate is an inhaled corticosteroid that reduces inflammation in the airways by inhibiting the release of inflammatory mediators from certain lung cells. Vilanterol is a long-acting beta2-adrenergic agonist (LABA) bronchodilator that relaxes airway smooth muscle, leading to bronchodilation and improved airflow. The combination improves lung function, reduces exacerbations, and helps control symptoms but does not treat acute attacks[1][2][3].

Brand names
Breo Ellipta
Other names
fluticasone and vilanterolfluticasone/vilanterol
02

Targets

CYP3A4 (Cytochrome P450 3A4)ABCB1 (P-glycoprotein)ADRB2 (β2)GR (Glucocorticoid receptor)

Beyond the preview

Go deeper on fluticasone propionate + vilanterol.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on fluticasone propionate + vilanterol.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call