fluticasone propionate + vitamin d

Fluticasone propionate + vitamin D is a combination of a synthetic glucocorticoid corticosteroid (fluticasone propionate) and a fat-soluble secosteroid (vitamin D, typically as cholecalciferol or ergocalciferol). Fluticasone propionate acts as an anti-inflammatory agent by binding to the glucocorticoid receptor, reducing inflammation in the airways or nasal passages. Vitamin D plays a role in calcium homeostasis and immune modulation. This combination has been studied for use in allergic rhinitis and asthma management; some studies suggest that adding vitamin D to standard intranasal or inhaled corticosteroid therapy may provide additional symptom relief for allergic rhinitis or improve regulatory effects on serum 25-hydroxyvitamin D levels in asthma patients[4][6][8]. However, this is not an approved fixed-dose pharmaceutical product but rather refers to concurrent administration of both agents. The mechanism involves anti-inflammatory action via glucocorticoid receptor agonism (fluticasone) and immunomodulatory effects through the nuclear hormone receptor family (vitamin D receptor).

Other names

fluticasone propionate and vitamin dfluticasone nasal and vitamin d3fluticasone with vitamin d