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Fluzone HD + Nuvaxovid

Development stage: Unknown
Lead developer: Sanofi
Modality: Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

SP0287 (Fluzone HD + Nuvaxovid) is a combination vaccine candidate developed by Sanofi in collaboration with Novavax. It combines Sanofi's Fluzone High-Dose Quadrivalent, an inactivated influenza vaccine designed for adults aged 65 and older, with Novavax's Nuvaxovid (NVX-CoV2373), a protein-based, adjuvanted COVID-19 vaccine. The combination aims to provide simultaneous protection against seasonal influenza and SARS-CoV-2. The vaccine utilizes Novavax's recombinant spike protein technology and Matrix-M adjuvant alongside Sanofi's high-dose hemagglutinin antigens to elicit a robust immune response in the elderly population. It is currently in Phase 1 clinical development.

Brand names: Fluzone HD + Nuvaxovid
Other names: SP0287SP-0287SP 0287Fluzone High-Dose Quadrivalent + Nuvaxovid

Targets

HA (Hemagglutinin)SARS-CoV-2 spike

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