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folic acid + cyanocobalamin

Development stage: Unknown
Modality: Small Molecules
Administration: Oral

Overview

**Folic acid + cyanocobalamin** is a fixed-dose vitamin combination containing folic acid, a synthetic form of vitamin B9, and cyanocobalamin, a form of vitamin B12. It is used as nutritional replacement or supplementation for folate and vitamin B12 deficiency states, supporting one-carbon metabolism, DNA synthesis, erythropoiesis, neurologic function, and homocysteine metabolism. Marketed oral products include prescription and nonprescription dietary-supplement formulations; the combination has also been evaluated as an adjunctive intervention in neuropsychiatric and cognitive disorders.

Brand names: Folic + B12FoltrateMTX SupportOpurity B12/Folic AcidVitamin B12-Folic Acid
Other names: cyanocobalamin + folic acidcyanocobalamin/folic acidfolic acid and cyanocobalaminfolic acid + cyanocobalamin

Targets

DHFR (Dihydrofolate reductase)MTR (Methionine synthase)FOLR1 (FRα)

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