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folic acid + penicillin
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Oral, Intravenous, Intramuscular
01
Overview
This combination refers to the concurrent use of folic acid (vitamin B9) and penicillin antibiotics. Penicillin derivatives can deplete folic acid levels in the body. Folic acid is a B vitamin used to treat folate deficiency, megaloblastic anemia, and prevent birth defects, while penicillin antibiotics are used to treat bacterial infections. When used together, monitoring of folate levels may be necessary, especially for long-term penicillin therapy.
02
Targets
DHFR (Dihydrofolate reductase)PBP (Penicillin-binding protein family)
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