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folic acid + vitamin B6 + methylcobalamin

Development stage: Unknown
Modality: Small Molecules
Administration: Intramuscular, Intravenous, Oral

Overview

The combination of folic acid (vitamin B9), vitamin B6 (pyridoxine), and methylcobalamin (vitamin B12) is a fixed-dose nutritional supplement and therapeutic combination used to treat and prevent vitamin B deficiencies, support cardiovascular health by lowering homocysteine levels, and manage neurological conditions such as peripheral neuropathy. Folic acid is essential for DNA synthesis and red blood cell production. Vitamin B6 is involved in amino acid metabolism and neurotransmitter synthesis. Methylcobalamin, an active form of vitamin B12, is crucial for nerve myelination, DNA synthesis, and red blood cell maturation. Together, these B vitamins act synergistically to support cellular metabolism, nervous system function, and cardiovascular health.

Brand names: FmpFolFolfitFolvite MBMevifMinalNuroday-HRejunuron ODTroynuronWincobal
Other names: folic acid + pyridoxine + methylcobalaminfolic acid + vitamin B6 + vitamin B12methylcobalamin + pyridoxine + folic acidmethylcobalamin + vitamin B6 + folic acidvitamin B6 + vitamin B12 + folic acid

Targets

PDXK (Pyridoxal kinase)FOLR1 (FRα)DHFR (Dihydrofolate reductase)MTR (Methionine synthase)PNPO (Pyridoxine 5'-phosphate oxidase)

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