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follitropin + sodium chloride + luteinizing hormone

Development stage
Unknown
Lead developer
Ferring Pharmaceuticals
Administration
Subcutaneous
01

Overview

**Follitropin + sodium chloride + luteinizing hormone** is a gonadotropin combination product corresponding in practice to menotropins for injection, supplied as follicle-stimulating hormone activity plus luteinizing hormone activity and reconstituted with sodium chloride for subcutaneous administration. Clinically, this combination is used in infertility treatment to stimulate ovarian follicular development in women undergoing ovulation induction or assisted reproductive technology. The pharmacologic effect is driven by exogenous FSH activity acting at the follicle-stimulating hormone receptor on ovarian granulosa cells and LH activity acting at the luteinizing hormone receptor on theca and related ovarian cells, thereby promoting follicular growth, steroidogenesis, and maturation of oocytes; sodium chloride functions as the diluent or formulation component rather than as the therapeutic driver. The marketed human pharmaceutical product most specifically matching this ingredient set is Menopur, developed and manufactured by Ferring for female infertility indications.

Brand names
Menopur
Other names
menotropins for injectionhuman menopausal gonadotropinsFSH + LH + sodium chloride
02

Targets

FSHR (Follicle-stimulating hormone receptor)LHCGR (Luteinizing hormone/choriogonadotropin receptor)

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