Drug intelligence / Profile preview

Folrex (0427a6)

Development stage
Phase 3
Lead developer
Catalysis
Modality
Small Molecules
Administration
Topical
01

Overview

Folrex is a therapeutic product line developed by Catalysis SL, featuring molecularly activated folic acid as its primary active component. The proprietary activation process is claimed to enhance the antioxidant and anti-inflammatory properties of the folic acid molecule. While widely available as a nutraceutical for managing joint pain and inflammation associated with arthritis, Folrex has been specifically studied in clinical settings for its potential to aid in the rehabilitation of stroke patients. A Phase 3 clinical trial investigated the use of Folrex cream to improve upper extremity motor function in patients undergoing rehabilitation following an acute stroke, based on the hypothesis that it reduces local oxidative stress and inflammation in affected tissues.

Brand names
Folrex
Other names
activated folic acid
02

Targets

FOLR1 (FRα)DHFR (Dihydrofolate reductase)

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